Margaret Hamilton, a profoundly influential computer scientist best known for leading the software engineering team at MIT’s Instrumentation Lab during NASA’s Apollo program, died on Sep. 30. She was 90.

A computing pioneer who authored over 130 publications, Hamilton helped to establish software engineering as a dedicated discipline. She worked at MIT from 1959 until the mid-1970s, after which she became a successful computing entrepreneur and CEO.

Her life’s work was recognized with many awards and honors, including the 2016 Presidential Medal of Freedom from President Barack Obama, whose citation noted: “Hamilton defined new forms of software engineering and helped launch an industry that would forever change human history. Her software architecture led to giant leaps for humankind, writing the code that helped America set foot on the moon.”